Phases of Bone Healing

Bone Stage 1

Woven callus formation is completed in about six weeks in humans.


Stage 2

Lamellar compaction is completed by week 18 through the deposition of lamellar bone which fills the lattice of woven bone callus. In the manner, composite bone is formed, which is much stronger and able to stabilize the implant.


Stage 3

Interface remodeling takes place to repair bone that is injured or damaged. Even during high-quality surgical placement of implants, there is some degree of damage at the bone interface. Interface remodeling starts once the implant is stabilized. It occurs at about the same time that the callus is being strengthen, and takes approximately 18 weeks to be completed in humans.


Stage 4

During the maturation phase, there is an increase in the mineral density of the tissue, which at the time of lay down is mineralized at about 65% of total mineral value. In humans, maturation is completed by about week 54 (one year).




Stage 5

Because an implant is not normal to adjacent bone, there is an ongoing process that has to occur in order to successfully maintain the implant in the tissue. There is a tremendously high turnover rate in bone adjacent to the implant surface compared to bone farther away from the implant.

Intense remodeling of lamellar bone within 1 mm of the implant surface is the mechanism by which rigid osseous fixation is sustained (osteointegration).



 Dr. Natalia Demianko

DDS / 2015